API reference

Trifluridine

CAS number
70-00-8
Molecular formula
C10H11F3N2O5
Molecular weight
296.2 g/mol
Trifluridine — 2D structure
2D structure (PubChem)

About this molecule

Trifluridine is a pyrimidine 2'-deoxyribonucleoside compound having 5-trifluoromethyluracil as the nucleobase. An antiviral drug used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis. It has a role as an antimetabolite, an antineoplastic agent, an antiviral drug and an EC 2.1.1.45 (thymidylate synthase) inhibitor. It is a pyrimidine 2'-deoxyribonucleoside, an organofluorine compound and a nucleoside analogue.

Source: ChEBI, via PubChem.

Identifiers

IUPAC name
1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(trifluoromethyl)pyrimidine-2,4-dione
InChIKey
VSQQQLOSPVPRAZ-RRKCRQDMSA-N
SMILES
C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)C(F)(F)F)CO)O
PubChem CID
6256

Also known as

Trifluridine · Viroptic · F3DThd · Trifluoromethyldeoxyuridine · Trifluridina · Trifluridinum · F3TDR · 5-(Trifluoromethyl)deoxyuridine

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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