API reference
Adapalene
- CAS number
- 106685-40-9
- Molecular formula
- C28H28O3
- Molecular weight
- 412.5 g/mol
About this molecule
Adapalene is a topical retinoid-like compound, chemically similar to vitamin A. Although the exact mechanism of action is unknown, adapalene binds to specific retinoic acid receptors in the nucleus, leading to specific gene expression. This agent stimulates skin growth through modulation of cellular differentiation, inflammatory processes and keratinization of follicular epithelial cells. Adapalene may increase dermal sensitivity to ultraviolet radiation. (NCI04)
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 6-[3-(1-adamantyl)-4-methoxyphenyl]naphthalene-2-carboxylic acid
- InChIKey
- LZCDAPDGXCYOEH-UHFFFAOYSA-N
- SMILES
- COC1=C(C=C(C=C1)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O)C45CC6CC(C4)CC(C6)C5
- PubChem CID
- 60164
Also known as
ADAPALENE · Differin · Adaferin · Adapaleno · CD-271 · Adapalenum · Differine · CD 271
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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