API reference
Allopurinol
- CAS number
- 315-30-0
- Molecular formula
- C5H4N4O
- Molecular weight
- 136.11 g/mol
About this molecule
Allopurinol is only found in individuals that have used or taken this drug. It is a xanthine oxidase inhibitor that decreases uric acid production. It also acts as an antimetabolite on some simpler organisms. [PubChem] Allopurinol and its active metabolite, oxypurinol, inhibits the enzyme xanthine oxidase, blocking the conversion of the oxypurines hypoxanthine and xanthine to uric acid. Elevated concentrations of oxypurine and oxypurine inhibition of xanthine oxidase through negative feedback results in a decrease in the concentrations of uric acid in the serum and urine. Allopurinol also facilitates the incorporation of hypoxanthine and xanthine into DNA and RNA, leading to a feedback inhibition of de novo purin synthesis and a decrease in serum uric acid concentrations as a result of an increase in nucleotide concentration.
Source: Toxin and Toxin Target Database (T3DB), via PubChem.
Identifiers
- IUPAC name
- 1,5-dihydropyrazolo[5,4-d]pyrimidin-4-one
- InChIKey
- OFCNXPDARWKPPY-UHFFFAOYSA-N
- SMILES
- C1=NNC2=C1C(=O)NC=N2
- Other CAS numbers recorded
- 180749-06-8 · 180749-08-0 · 73334-58-4 · 180749-09-1
- PubChem CID
- 135401907
Also known as
allopurinol · Zyloric · Takanarumin · Suspendol · Allopur · Bloxanth · Uriprim · Xanturat
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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