API reference
Alprazolam
- CAS number
- 28981-97-7
- Molecular formula
- C17H13ClN4
- Molecular weight
- 308.8 g/mol
About this molecule
Alprazolam is a triazolobenzodiazepine agent with anxiolytic, sedative-hypnotic and anticonvulsant activities. Alprazolam binds to a specific site distinct from the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) binding site on the benzodiazepine-GABA-A-chloride ionophore receptor complex located in the limbic, thalamic and hypothalamic regions of the central nervous system (CNS). This binding causes an allosteric modification of the receptor and enhances the affinity of GABA to the receptor leading to an increase in the frequency of chloride-channel opening events. This leads to an increase in chloride ion conductance, neuronal hyperpolarization, inhibition of the action potential and leads to a decrease in neuronal excitability.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 8-chloro-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
- InChIKey
- VREFGVBLTWBCJP-UHFFFAOYSA-N
- SMILES
- CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4
- Other CAS numbers recorded
- 51339-48-1 · 1246182-61-5
- PubChem CID
- 2118
Also known as
alprazolam · Xanax · Niravam · Solanax · Tranquinal · Alplax · Xanor · Alpronax
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