API reference

Alprostadil

CAS number
745-65-3
Molecular formula
C20H34O5
Molecular weight
354.5 g/mol
Alprostadil — 2D structure
2D structure (PubChem)

About this molecule

Alprostadil is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Alprostadil is a potent vasodilator agent that increases peripheral blood flow, inhibits platelet aggregation, and induces bronchodilation. Used in the treatment of erectile dysfunction, this agent produces corporal smooth muscle relaxation by binding to PGE receptors, resulting in the activation of adenylate cyclase and the subsequent accumulation of 3'5'-cAMP.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid
InChIKey
GMVPRGQOIOIIMI-DWKJAMRDSA-N
SMILES
CCCCC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1CCCCCCC(=O)O)O)O
PubChem CID
5280723

Also known as

alprostadil · Prostaglandin E1 · PGE1 · Caverject · Edex · Muse · Alprostadilum · Befar

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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