API reference

Ambroxol

CAS number
18683-91-5
Molecular formula
C13H18Br2N2O
Molecular weight
378.1 g/mol
Ambroxol — 2D structure
2D structure (PubChem)

About this molecule

Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the respiratory tract which play an important role in the body’s natural defence mechanisms. It stimulates synthesis and release of surfactant by type II pneumocytes. Surfactants acts as an anti-glue factor by reducing the adhesion of mucus to the bronchial wall, in improving its transport and in providing protection against infection and irritating agents.

Source: DrugBank, via PubChem.

Identifiers

IUPAC name
4-[(2-amino-3,5-dibromophenyl)methylamino]cyclohexan-1-ol
InChIKey
JBDGDEWWOUBZPM-UHFFFAOYSA-N
SMILES
C1CC(CCC1NCC2=C(C(=CC(=C2)Br)Br)N)O
Other CAS numbers recorded
107814-37-9 · 36557-04-7 · 1217679-83-8
PubChem CID
2132

Also known as

ambroxol · rac-cis-Ambroxol · Ambroxol EP Impurity D · 4-((2-amino-3,5-dibromobenzyl)amino)cyclohexan-1-ol · cis-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol · Bisolvon metabolite VIII · Bromhexine-metabolite VIII · NA-872

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