API reference
Aminophylline
- CAS number
- 317-34-0
- Molecular formula
- C16H24N10O4
- Molecular weight
- 420.43 g/mol
About this molecule
Aminophylline is a methylxanthine and derivative of theophylline. Aminophylline relaxes smooth muscles, particularly bronchial muscles. This xanthine most likely exerts its effect by inhibiting cAMP or cGMP phosphodiesterases, thereby increasing levels of the second messenger cAMP or cGMP intracellularly. Other mode of actions include an adenosine antagonistic effect on the activity of CD4 lymphocytes and mediator release from mast cells thereby decreasing lung sensitivity to allergens and other substances that cause inflammation. Aminophylline also acts as a CNS stimulant and exerts a positive chronotropic and inotropic effect on the heart.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- bis(1,3-dimethyl-7H-purine-2,6-dione);ethane-1,2-diamine
- InChIKey
- FQPFAHBPWDRTLU-UHFFFAOYSA-N
- SMILES
- CN1C2=C(C(=O)N(C1=O)C)NC=N2.CN1C2=C(C(=O)N(C1=O)C)NC=N2.C(CN)N
- Other CAS numbers recorded
- 95646-60-9
- PubChem CID
- 9433
Also known as
aminophylline · Aminophyllin · Cardophyllin · Linampheta · Phyllocontin · Syntophyllin · Truphylline · Ethophylline
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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