API reference
AMIODARONE HCl
- CAS number
- 19774-82-4
- Molecular formula
- C25H30ClI2NO3
- Molecular weight
- 681.8 g/mol
About this molecule
Amiodarone Hydrochloride is the hydrochloride salt of an iodine-rich benzofuran derivative with antiarrhythmic and vasodilatory activities. As a class III antiarrhythmic agent, amiodarone blocks the myocardial calcium, potassium and sodium channels in cardiac tissue, resulting in prolongation of the cardiac action potential and refractory period. In addition, this agent inhibits alpha- and beta-adrenergic receptors, resulting in a reduction in sympathetic stimulation of the heart, a negative chronotropic effect, and a decrease in myocardial oxygen demands. Amiodarone may cause vasodilation by stimulation of the release of nitric oxide and cyclooxygenase-dependent relaxing endothelial factors.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (2-butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone;hydrochloride
- InChIKey
- ITPDYQOUSLNIHG-UHFFFAOYSA-N
- SMILES
- CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCCN(CC)CC)I.Cl
- PubChem CID
- 441325
Also known as
Amiodarone hydrochloride · Amiodarone HCL · Nexterone · Amiodar · Ritmocardyl · Pacerone · Miodaron · Ortacrone
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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