API reference
Amlodipine besilate
- CAS number
- 111470-99-6
- Molecular formula
- C26H31ClN2O8S
- Molecular weight
- 567.1 g/mol
About this molecule
Amlodipine Besylate is the besylate salt of amlodipine, a synthetic dihydropyridine with antihypertensive and antianginal effects. Amlodipine inhibits the influx of extracellular calcium ions into myocardial and peripheral vascular smooth muscle cells, thereby preventing vascular and myocardial contraction. This results in a dilatation of the main coronary and systemic arteries, decreased myocardial contractility, increased blood flow and oxygen delivery to the myocardial tissue, and decreased total peripheral resistance. This agent may also modulate multi-drug resistance (MDR) activity through inhibition of the p-glycoprotein efflux pump.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- benzenesulfonic acid;3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
- InChIKey
- ZPBWCRDSRKPIDG-UHFFFAOYSA-N
- SMILES
- CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C1=CC=C(C=C1)S(=O)(=O)O
- PubChem CID
- 60496
Also known as
AMLODIPINE BESYLATE · Amlodipine besilate · Amlodipine benzenesulfonate · Antacal · Monopina · Norvas · Lodipressin · NORLIQVA
Related entries in the range
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