API reference
Amodiaquine
- CAS number
- 86-42-0
- Molecular formula
- C20H22ClN3O
- Molecular weight
- 355.9 g/mol
About this molecule
Amodiaquine is an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory properties. Similar in structure and activity to chloroquine, amodiaquine is effective against some chloroquine-resistant strains, particularly Plasmodium falciparum, the most deadly malaria parasite. Although the mechanism of plasmodicidal action has not been fully elucidated, like other quinoline derivatives, amodiaquine likely is able to inhibit heme polymerase activity in the body. This results in accumulation of free heme, which is toxic to the parasites.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol
- InChIKey
- OVCDSSHSILBFBN-UHFFFAOYSA-N
- SMILES
- CCN(CC)CC1=C(C=CC(=C1)NC2=C3C=CC(=CC3=NC=C2)Cl)O
- Other CAS numbers recorded
- 1021496-19-4
- PubChem CID
- 2165
Also known as
amodiaquine · Amodiaquin · Flavoquine · Camoquin · Camochin · Camoquinal · Miaquin · Amodiachinum
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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