API reference
Anastrozole
- CAS number
- 120511-73-1
- Molecular formula
- C17H19N5
- Molecular weight
- 293.4 g/mol
About this molecule
Anastrozole is a non-steroidal aromatase inhibitor (AI), similar to [letrozole], used to decrease circulating estrogen levels in the treatment of postmenopausal women with estrogen-responsive breast cancer. Anastrozole is also related to [exemestane], a steroidal AI, but its non-steroidal nature provides stark advantages including a lack of steroid-associated adverse effects such as weight gain and acne. Aromatase inhibitors, including anastrozole, have become endocrine drugs of choice in the treatment of postmenopausal breast cancer due to a more favourable efficacy and adverse effect profile as compared to earlier estrogen receptor modulators such as [tamoxifen]. Anastrozole was first approved for use in the United States in 1995.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- 2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile
- InChIKey
- YBBLVLTVTVSKRW-UHFFFAOYSA-N
- SMILES
- CC(C)(C#N)C1=CC(=CC(=C1)CN2C=NC=N2)C(C)(C)C#N
- PubChem CID
- 2187
Also known as
anastrozole · Arimidex · anastrazole · Anastrozol · anastrozolum · Nastrosa · Anastrozole Tablets · L02BG03
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
Tell us the grade, the quantity and the market.
Send the molecule or ingredient, the specification and the destination. We reply from Tehran with the questions, the documents and the next step.