API reference

Arformoterol tartrate

CAS number
200815-49-2
Molecular formula
C23H30N2O10
Molecular weight
494.5 g/mol
Arformoterol tartrate — 2D structure
2D structure (PubChem)

About this molecule

Arformoterol Tartrate is the tartrate salt of arformoterol, the (R,R)-enantiomer of formoterol and a long-acting beta-2 adrenergic agonist with bronchodilator activity. Arformoterol selectively binds to and activates beta-2 adrenergic receptors in bronchiolar smooth muscle, thereby causing stimulation of adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased intracellular cAMP levels cause relaxation of bronchial smooth muscle and lead to an inhibition of release of inflammatory mediators from mast cells. This may eventually lead to an improvement of airway function.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
(2R,3R)-2,3-dihydroxybutanedioic acid;N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino]ethyl]phenyl]formamide
InChIKey
FCSXYHUNDAXDRH-OKMNHOJOSA-N
SMILES
C[C@H](CC1=CC=C(C=C1)OC)NC[C@@H](C2=CC(=C(C=C2)O)NC=O)O.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O
PubChem CID
9827062

Also known as

Arformoterol tartrate · Brovana · (R,R)-Arformoterol tartrate · ARFORMOTEROL TARTRATE (MART.) · Formoterol r,r-form l-tartrate · Arformoterol Tartrate Inhalation · Arformoterol Tartrate Inhalation Solution · Arformoterol tartrate (USAN)

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