API reference
Aripiprazole
- CAS number
- 129722-12-9
- Molecular formula
- C23H27Cl2N3O2
- Molecular weight
- 448.4 g/mol
About this molecule
Aripiprazole is an atypical antipsychotic medication used for the treatment of schizophrenia. It has also recently received FDA approval for the treatment of acute manic and mixed episodes associated with bipolar disorder. Aripiprazole appears to mediate its antipsychotic effects primarily by partial agonism at the D2 receptor. In addition to partial agonist activity at the D2 receptor, aripiprazole is also a partial agonist at the 5-HT1A receptor, and like the other atypical antipsychotics, aripiprazole displays an antagonist profile at the 5-HT2A receptor. Aripiprazole has moderate affinity for histamine and alpha adrenergic receptors, and no appreciable affinity for cholinergic muscarinic receptors.
Source: Toxin and Toxin Target Database (T3DB), via PubChem.
Identifiers
- IUPAC name
- 7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
- InChIKey
- CEUORZQYGODEFX-UHFFFAOYSA-N
- SMILES
- C1CC(=O)NC2=C1C=CC(=C2)OCCCCN3CCN(CC3)C4=C(C(=CC=C4)Cl)Cl
- Other CAS numbers recorded
- 1026778-41-5 · 24-29-3
- PubChem CID
- 60795
Also known as
Aripiprazole · Abilify · Abilitat · Abilify Discmelt · aripiprazol · Discmelt · Aripiprex · Abilify MyCite
Related entries in the range
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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