API reference

Artemether

CAS number
71963-77-4
Molecular formula
C16H26O5
Molecular weight
298.37 g/mol
Artemether — 2D structure
2D structure (PubChem)

About this molecule

Artemether is an artemisinin derivative that is artemisinin in which the lactone has been converted to the corresponding lactol methyl ether. It is used in combination with lumefantrine as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. It has a role as an antimalarial. It is an organic peroxide, a sesquiterpenoid, a cyclic acetal, an artemisinin derivative and a semisynthetic derivative.

Source: ChEBI, via PubChem.

Identifiers

IUPAC name
(1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane
InChIKey
SXYIRMFQILZOAM-HVNFFKDJSA-N
SMILES
C[C@@H]1CC[C@H]2[C@H]([C@H](O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C)OC)C
PubChem CID
68911

Also known as

Artemether · beta-Artemether · Dihydroartemisinin methyl ether · Artemetero · Artemetherum · Artesaph · Falcidol · Gvither

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