API reference
Atorvastatin calcium
- CAS number
- 134523-03-8
- Molecular formula
- C66H68CaF2N4O10
- Molecular weight
- 1,155.3 g/mol
About this molecule
Atorvastatin (Lipitor) is a member of the drug class known as statins. It is used for lowering cholesterol. Atorvastatin is a competitive inhibitor of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, the rate-determining enzyme in cholesterol biosynthesis via the mevalonate pathway. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonate. Atorvastatin acts primarily in the liver. Decreased hepatic cholesterol levels increases hepatic uptake of cholesterol and reduces plasma cholesterol levels.
Source: Toxin and Toxin Target Database (T3DB), via PubChem.
Identifiers
- IUPAC name
- calcium bis((3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate)
- InChIKey
- FQCKMBLVYCEXJB-MNSAWQCASA-L
- SMILES
- CC(C)C1=C(C(=C(N1CC[C@H](C[C@H](CC(=O)[O-])O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.CC(C)C1=C(C(=C(N1CC[C@H](C[C@H](CC(=O)[O-])O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.[Ca+2]
- Other CAS numbers recorded
- 363599-71-7 · 1316891-47-0
- PubChem CID
- 60822
Also known as
ATORVASTATIN CALCIUM · Tahor · Atorvastatin calcium anhydrous · CI-981 · Liprimar · Atorvastatin calcium (anhydrous) · Atorvastatin calcium salt anhydrous · Dengue Kill
Related entries in the range
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