API reference
Avatrombopag maleate
- CAS number
- 677007-74-8
- Molecular formula
- C33H38Cl2N6O7S2
- Molecular weight
- 765.7 g/mol
About this molecule
Avatrombopag Maleate is the maleate salt form of avatrombopag, an orally available platelet thrombopoietin receptor (TPOR; MPL) agonist, with potential megakaryopoiesis stimulating activity. Upon administration, avatrombopag binds to and stimulates TPOR, which may lead to the proliferation and differentiation of megakaryocytes from bone marrow progenitor cells. This increases the production of platelets and may prevent chemotherapy-induced thrombocytopenia (CIT). TPOR is a cytokine receptor and member of the hematopoietin receptor superfamily.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (Z)-but-2-enedioic acid;1-[3-chloro-5-[[4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)-1,3-thiazol-2-yl]carbamoyl]-2-pyridinyl]piperidine-4-carboxylic acid
- InChIKey
- MISPBGHDNZYFNM-BTJKTKAUSA-N
- SMILES
- C1CCC(CC1)N2CCN(CC2)C3=C(N=C(S3)NC(=O)C4=CC(=C(N=C4)N5CCC(CC5)C(=O)O)Cl)C6=CC(=CS6)Cl.C(=C\C(=O)O)\C(=O)O
- PubChem CID
- 9918581
Also known as
Avatrombopag maleate · Avatrombopag (maleate) · Avatrombopag Meleate · Doptelet (TN) · Avatrombopag maleate? · AKR-501 monomaleate · C33H38Cl2N6O7S2 · Avatrombopag maleate (JAN/USAN)
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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