API reference
Azelaic acid
- CAS number
- 123-99-9
- Molecular formula
- C9H16O4
- Molecular weight
- 188.22 g/mol
About this molecule
Azelaic Acid is a naturally occurring dicarboxylic acid produced by Malassezia furfur and found in whole grain cereals, rye, barley and animal products. Azelaic acid possesses antibacterial, keratolytic, comedolytic, and anti-oxidant activity. Azelaic acid is bactericidal against Proprionibacterium acnes and Staphylococcus epidermidis due to its inhibitory effect on the synthesis of microbial cellular proteins. Azelaic acid exerts its keratolytic and comedolytic effects by reducing the thickness of the stratum corneum and decreasing the number of keratohyalin granules by reducing the amount and distribution of filaggrin in epidermal layers. Azelaic acid also possesses a direct anti-inflammatory effect due to its scavenger activity of free oxygen radical. This drug is used topically to reduce inflammation associated with acne and rosacea.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- nonanedioic acid
- InChIKey
- BDJRBEYXGGNYIS-UHFFFAOYSA-N
- SMILES
- C(CCCC(=O)O)CCCC(=O)O
- PubChem CID
- 2266
Also known as
azelaic acid · NONANEDIOIC ACID · Finacea · Anchoic acid · Lepargylic acid · Azelex · 1,7-Heptanedicarboxylic acid · Skinoren
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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