API reference
Baclofen
- CAS number
- 1134-47-0
- Molecular formula
- C10H12ClNO2
- Molecular weight
- 213.66 g/mol
About this molecule
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the FDA in 1977. Baclofen is used to manage severe muscle spasms of cerebral or spinal cord origins, including multiple sclerosis and traumatic brain injury. Baclofen was investigated for use in alcohol dependence and withdrawal; however, evidence is limited and there is inconsistent evidence to suggest its clinical efficacy in managing alcohol dependence or withdrawal symptoms.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- 4-amino-3-(4-chlorophenyl)butanoic acid
- InChIKey
- KPYSYYIEGFHWSV-UHFFFAOYSA-N
- SMILES
- C1=CC(=CC=C1C(CC(=O)O)CN)Cl
- PubChem CID
- 2284
Also known as
baclofen · Lioresal · 4-Amino-3-(4-chlorophenyl)butanoic acid · Kemstro · Baclon · DL-Baclofen · Baclofene · Baclofeno
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
Tell us the grade, the quantity and the market.
Send the molecule or ingredient, the specification and the destination. We reply from Tehran with the questions, the documents and the next step.