API reference

Benzonatate

CAS number
104-31-4
Molecular formula
C30H53NO11
Molecular weight
603.7 g/mol
Benzonatate — 2D structure
2D structure (PubChem)

About this molecule

Benzonatate is an oral antitussive drug used in the relief and suppression of cough in patients older than ten years of age. Currently, benzonatate is the only non-narcotic antitussive available as a prescription drug. It works to reduce the activity of cough reflex by desensitizing the tissues of the lungs and pleura involved in the cough reflex. Benzonatate was approved by the FDA in 1958 under the market name Tessalon Perles. Because its chemical structure resembles that of the anesthetic agents in the para-amino-benzoic acid class (such as [procaine] and [tetracaine]), benzonatate exhibits anesthetic or numbing action. Although it not prone to drug misuse or abuse, benzonatate is associated with a risk for severe toxicity and overdose, especially in children.

Source: DrugBank, via PubChem.

Identifiers

IUPAC name
2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-(butylamino)benzoate
InChIKey
MAFMQEKGGFWBAB-UHFFFAOYSA-N
SMILES
CCCCNC1=CC=C(C=C1)C(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCOC
PubChem CID
7699

Also known as

Benzonatate · Benzononatine · Tessalon · Benzonatatum · Benzonatato · Tessalon Perles · Zonatuss · nonaethyleneglycol monomethyl ether p-n-butylaminobenzoate

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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