API reference

Betamethasone

CAS number
378-44-9
Molecular formula
C22H29FO5
Molecular weight
392.5 g/mol
Betamethasone — 2D structure
2D structure (PubChem)

About this molecule

Betamethasone is a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory activities. Betamethasone binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
InChIKey
UREBDLICKHMUKA-DVTGEIKXSA-N
SMILES
C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C
PubChem CID
9782

Also known as

betamethasone · Betadexamethasone · Flubenisolone · Rinderon · Visubeta · Celestene · Betnelan · Desacort-Beta

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