API reference
Bisoprolol fumarate
- CAS number
- 104344-23-2
- Molecular formula
- C40H66N2O12
- Molecular weight
- 767 g/mol
About this molecule
Bisoprolol Fumarate is the fumarate salt of a synthetic phenoxy-2-propanol-derived cardioselective beta-1 adrenergic receptor antagonist with antihypertensive and potential cardioprotective activities. Devoid of intrinsic sympathomimetic activity, bisoprolol selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart, decreasing cardiac contractility and rate, reducing cardiac output, and lowering blood pressure. In addition, this agent may exhibit antihypertensive activity through the inhibition of renin secretion by juxtaglomerular epithelioid (JGE) cells in the kidney, thus inhibiting activation of the renin-angiotensin system (RAS). Bisoprolol has been shown to be cardioprotective in animal models.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (E)-but-2-enedioic acid;bis(1-(propan-2-ylamino)-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]propan-2-ol)
- InChIKey
- VMDFASMUILANOL-WXXKFALUSA-N
- SMILES
- CC(C)NCC(COC1=CC=C(C=C1)COCCOC(C)C)O.CC(C)NCC(COC1=CC=C(C=C1)COCCOC(C)C)O.C(=C/C(=O)O)\C(=O)O
- PubChem CID
- 5281064
Also known as
Bisoprolol fumarate · Bisoprolol hemifumarate · Zebeta · Detensiel · Isoten · Euradal · Monocor · Soprol
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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