API reference

Brinzolamide

CAS number
138890-62-7
Molecular formula
C12H21N3O5S3
Molecular weight
383.5 g/mol
Brinzolamide — 2D structure
2D structure (PubChem)

About this molecule

Brinzolamide is a sulfonamide and carbonic anhydrase inhibitor with specific affinity for carbonic anhydrase II. Following topical ocular administration, brinzolamide inhibits carbonic anhydrase II, an enzyme that is responsible for the movement of sodium and fluid transport in the eye. This inhibition leads to a decrease in aqueous humor secretion, probably by slowing the formation of bicarbonate ions, and results in a reduction in intraocular pressure. Brinzolamide is used to treat increased pressure in the eye caused by open-angle glaucoma.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
(4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-3,4-dihydrothieno[3,2-e]thiazine-6-sulfonamide
InChIKey
HCRKCZRJWPKOAR-JTQLQIEISA-N
SMILES
CCN[C@H]1CN(S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)CCCOC
Other CAS numbers recorded
138890-50-3
PubChem CID
68844

Also known as

Brinzolamide · Azopt · Brinzolamida · AZARGA COMPONENT BRINZOLAMIDE · SIMBRINZA COMPONENT BRINZOLAMIDE · brinzolamidum · S01EC04 · Birnzolamide

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