API reference

Brivaracetam

CAS number
357336-20-0
Molecular formula
C11H20N2O2
Molecular weight
212.29 g/mol
Brivaracetam — 2D structure
2D structure (PubChem)

About this molecule

Brivaracetam is an orally bioavailable levetiracetam derivative, with anticonvulsant activity. Although the exact mechanism through which brivaracetam exerts its effects is not fully known, this agent targets and binds to synaptic vesicle protein 2A (SV2A) in the brain. This prevents synaptic vesicle exocytosis and the synaptic release of certain, as of yet not fully known, excitatory neurotransmitters. This may inhibit impulse conduction across synapses, decrease neuronal (hyper-)excitability, and may modulate epileptogenesis. SV2A, a membrane glycoprotein present in neuronal synaptic vesicles, plays a key role in action potential-induced neurotransmitter release in the brain.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
(2S)-2-[(4R)-2-oxo-4-propylpyrrolidin-1-yl]butanamide
InChIKey
MSYKRHVOOPPJKU-BDAKNGLRSA-N
SMILES
CCC[C@@H]1CC(=O)N(C1)[C@@H](CC)C(=O)N
PubChem CID
9837243

Also known as

Brivaracetam · Briviact · brivaracetamum · (2S)-2-((4R)-2-Oxo-4-propylpyrrolidin-1-yl)butanamide · N03AX23 · Rikelta · 2-(2-oxo-4-propylpyrrolidin-1-yl)butanamide · (S)-2-((R)-2-Oxo-4-propylpyrrolidin-1-yl)butanamide

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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