API reference
Bupivacaine
- CAS number
- 2180-92-9
- Molecular formula
- C18H28N2O
- Molecular weight
- 288.4 g/mol
About this molecule
Liposomal Bupivacaine is a liposome-encapsulated formulation of bupivacaine, which is an amide-type, long-acting local anesthetic. Upon administration, bupivacaine reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in both a decrease in the voltage-dependent membrane permeability to sodium ions and membrane stabilization. This leads to inhibition of both depolarization and nerve impulse conduction, and a reversible loss of sensation. Compared to bupivacaine alone, liposomal delivery increases the duration of local anesthetic action and delays the peak plasma concentration of bupivacaine due to its slow release from the liposome.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
- InChIKey
- LEBVLXFERQHONN-UHFFFAOYSA-N
- SMILES
- CCCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C
- Other CAS numbers recorded
- 38396-39-3 · 119427-31-5
- PubChem CID
- 2474
Also known as
Bupivacaine (USAN:INN:BAN) · bupivacaine · 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide · DL-Bupivacaine · Bupivacaina · Anekain · Bupivacainum · (+-)-Bupivacaine
Related entries in the range
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