API reference
BUPRENORPHINE HCl
- CAS number
- 53152-21-9
- Molecular formula
- C29H42ClNO4
- Molecular weight
- 504.1 g/mol
About this molecule
Buprenorphine Hydrochloride is the hydrochloride salt form of buprenorphine, a synthetic phenanthrene with narcotic analgesic activity. Buprenorphine hydrochloride is a partial agonist at the mu-opioid receptor and an antagonist at the kapa-opioid receptor in the central nervous system. However, under the conditions of recommended use it behaves as a classic mu-opioid agonist, mimicking the actions of endogenous peptides at CNS opioid receptors. The agonist action results in a raised pain threshold and increased tolerance to pain. However, it also causes sedation, physical dependence, and respiratory depressant effects and decreases heart rate and blood pressure.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol;hydrochloride
- InChIKey
- UAIXRPCCYXNJMQ-RZIPZOSSSA-N
- SMILES
- C[C@]([C@H]1C[C@@]23CC[C@@]1([C@H]4[C@@]25CCN([C@@H]3CC6=C5C(=C(C=C6)O)O4)CC7CC7)OC)(C(C)(C)C)O.Cl
- PubChem CID
- 3033050
Also known as
BUPRENORPHINE HYDROCHLORIDE · Finibron · Belbuca · Buprenorphine Hcl · Buprex · Vetergesic · Anorfin · Buprederm
Related entries in the range
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