API reference
Canagliflozin
- CAS number
- 842133-18-0
- Molecular formula
- C24H25FO5S
- Molecular weight
- 444.5 g/mol
About this molecule
Canagliflozin, also known as Invokana, is a sodium-glucose cotransporter 2 (SGLT2) inhibitor used in the management of type 2 diabetes mellitus along with lifestyle changes including diet and exercise. It was initially approved by the FDA in 2013 for the management of diabetes and later approved in 2018 for a second indication of reducing the risk of cardiovascular events in patients diagnosed with type 2 diabetes mellitus,. Canagliflozin is the first oral antidiabetic drug approved for the prevention of cardiovascular events in patients with type 2 diabetes. Cardiovascular disease is the most common cause of death in these patients.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- (2S,3R,4R,5S,6R)-2-[3-[[5-(4-fluorophenyl)thiophen-2-yl]methyl]-4-methylphenyl]-6-(hydroxymethyl)oxane-3,4,5-triol
- InChIKey
- XTNGUQKDFGDXSJ-ZXGKGEBGSA-N
- SMILES
- CC1=C(C=C(C=C1)[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CC3=CC=C(S3)C4=CC=C(C=C4)F
- Other CAS numbers recorded
- 928672-86-0
- PubChem CID
- 24812758
Also known as
Canagliflozin · Invokana · Canagliflozin anhydrous · Canagliflozina · Canagliflozine · Canagliflozin, Anhydrous · INVOKAMET COMPONENT CANAGLIFLOZIN · canagliflozinum
Related entries in the range
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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