API reference
Captopril
- CAS number
- 62571-86-2
- Molecular formula
- C9H15NO3S
- Molecular weight
- 217.29 g/mol
About this molecule
Captopril is a sulfhydryl-containing analog of proline with antihypertensive activity and potential antineoplastic activity. Captopril competitively inhibits angiotensin converting enzyme (ACE), thereby decreasing levels of angiotensin II, increasing plasma renin activity, and decreasing aldosterone secretion. This agent may also inhibit tumor angiogenesis by inhibiting endothelial cell matrix metalloproteinases (MMPs) and endothelial cell migration. Captopril may also exhibit antineoplastic activity independent of effects on tumor angiogenesis. (NCI04)
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
- InChIKey
- FAKRSMQSSFJEIM-RQJHMYQMSA-N
- SMILES
- C[C@H](CS)C(=O)N1CCC[C@H]1C(=O)O
- PubChem CID
- 44093
Also known as
captopril · Capoten · L-Captopril · Captopryl · Acepress · Captoril · Cesplon · Garranil
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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