API reference

Carvedilol

CAS number
72956-09-3
Molecular formula
C24H26N2O4
Molecular weight
406.5 g/mol
Carvedilol — 2D structure
2D structure (PubChem)

About this molecule

Carvedilol is a synthetic antihypertensive methoxyphenoxy- 2-propanol derivative with no intrinsic sympathomimetic activity, Carvedilol acts as a nonselective beta-adrenoceptor blocking agent (S(-) enantiomer) and as an alpha 1-adrenoceptor blocker (R(+) and S(-) enantiomers). Its acts more strongly on beta-receptors than on alpha 1-receptors, reduces peripheral vascular resistance by vasodilation, and prevents reflex tachycardia (beta-blockade) so that heart rate is either unchanged or decreased. Carvedilol also reduces renin release through beta-blockade. (NCI04)

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
InChIKey
OGHNVEJMJSYVRP-UHFFFAOYSA-N
SMILES
COC1=CC=CC=C1OCCNCC(COC2=CC=CC3=C2C4=CC=CC=C4N3)O
Other CAS numbers recorded
107741-96-8
PubChem CID
2585

Also known as

carvedilol · Coreg · Dilatrend · Eucardic · Carvedilolum · Artist · Kredex · Dimitone

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