API reference
Cefaclor
- CAS number
- 53994-73-3
- Molecular formula
- C15H14ClN3O4S
- Molecular weight
- 367.8 g/mol

About this molecule
Cefaclor is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. Cefaclor binds to and inactivates penicillin-binding proteins (PBP) located in bacterial cytoplasmic membranes. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- InChIKey
- QYIYFLOTGYLRGG-GPCCPHFNSA-N
- SMILES
- C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)C(=O)O)Cl
- Other CAS numbers recorded
- 143059-69-2
- PubChem CID
- 51039
Also known as
cefaclor · Ceclor · Cephaclor · Cefaclor anhydrous · Cefaclorum · Raniclor · Ceclor CD · Keftid
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