API reference

Cefaclor

CAS number
53994-73-3
Molecular formula
C15H14ClN3O4S
Molecular weight
367.8 g/mol
Cefaclor — 2D structure
2D structure (PubChem)

About this molecule

Cefaclor is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. Cefaclor binds to and inactivates penicillin-binding proteins (PBP) located in bacterial cytoplasmic membranes. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
(6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChIKey
QYIYFLOTGYLRGG-GPCCPHFNSA-N
SMILES
C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)C(=O)O)Cl
Other CAS numbers recorded
143059-69-2
PubChem CID
51039

Also known as

cefaclor · Ceclor · Cephaclor · Cefaclor anhydrous · Cefaclorum · Raniclor · Ceclor CD · Keftid

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