API reference

Cefixime

CAS number
79350-37-1
Molecular formula
C16H15N5O7S2
Molecular weight
453.5 g/mol
Cefixime — 2D structure
2D structure (PubChem)

About this molecule

Cefixime is a broad-spectrum, third-generation cephalosporin antibiotic derived semisynthetically from the marine fungus Cephalosporium acremonium with antibacterial activity. As does penicillin, the beta-lactam antibiotic cefixime inhibits bacterial cell wall synthesis by disrupting peptidoglycan synthesis, resulting in a reduction in bacterial cell wall stability and bacterial cell lysis. Stable in the presence of a variety of beta-lactamases, this agent is more active against gram-negative bacteria and less active against gram-positive bacteria compared to second-generation cephalosporins.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(carboxymethoxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChIKey
OKBVVJOGVLARMR-QSWIMTSFSA-N
SMILES
C=CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\OCC(=O)O)/C3=CSC(=N3)N)SC1)C(=O)O
PubChem CID
5362065

Also known as

CEFIXIME · Cefspan · Cephoral · Cefixima · Cefixime Anhydrous · Cefiximum · Oroken · Suprax

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