API reference
Cefotaxime
- CAS number
- 63527-52-6
- Molecular formula
- C16H17N5O7S2
- Molecular weight
- 455.5 g/mol
About this molecule
Cefotaxime is a third generation semisynthetic cephalosporin antibiotic with bactericidal activity. Cefotaxime inhibits mucopeptide synthesis by binding to and inactivating penicillin binding proteins thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of bacterial cell walls. This results in a reduction of cell wall stability and causes cell lysis.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- InChIKey
- GPRBEKHLDVQUJE-QSWIMTSFSA-N
- SMILES
- CC(=O)OCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\OC)/C3=CSC(=N3)N)SC1)C(=O)O
- Other CAS numbers recorded
- 60846-21-1 · 1056874-43-1 · 219827-56-2
- PubChem CID
- 5742673
Also known as
cefotaxime · Cephotaxime · Cefotaxima · Cefotaximum · Cefotaxim Hikma · Cephotaxim · Klaforan · Primafen
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