API reference
Celecoxib
- CAS number
- 169590-42-5
- Molecular formula
- C17H14F3N3O2S
- Molecular weight
- 381.4 g/mol
About this molecule
Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in the colon. It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval in 1998. Interestingly, selective COX-2 inhibitors (especially celecoxib), have been evaluated as potential cancer chemopreventive and therapeutic drugs in clinical trials for a variety of malignancies.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- 4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
- InChIKey
- RZEKVGVHFLEQIL-UHFFFAOYSA-N
- SMILES
- CC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F
- Other CAS numbers recorded
- 184007-95-2 · 194044-54-7
- PubChem CID
- 2662
Also known as
celecoxib · Celebrex · Celebra · Onsenal · Celecoxibum · YM 177 · ELYXYB · DFN15
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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