API reference

CEVIMELINE HCl

CAS number
153504-70-2
Molecular formula
C20H38Cl2N2O3S2
Molecular weight
489.6 g/mol
CEVIMELINE HCl — 2D structure
2D structure (PubChem)

About this molecule

Cevimeline Hydrochloride is a cholinergic analogue with glandular secretion stimulatory activity. Cevimeline binds to and activates muscarinic receptors, thereby increasing the secretions in exocrine salivary and sweat glands. This cholinergic agonist also increases the tone of smooth muscle in the gastrointestinal and urinary tracts. Cevimeline is being studied as a treatment for dry mouth caused by radiation therapy to the head and neck.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
bis((2S,5S)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane]);hydrate;dihydrochloride
InChIKey
ZSTLCHCDLIUXJE-ZGBAEQJLSA-N
SMILES
C[C@H]1O[C@@]2(CN3CCC2CC3)CS1.C[C@H]1O[C@@]2(CN3CCC2CC3)CS1.O.Cl.Cl
Other CAS numbers recorded
1462862-74-3
PubChem CID
73416227

Also known as

AF102B · Cevimeline HCl · Saligren · FKS-508 · SNK-508 · cevimeline hydrochloride hydrate · AF 102B · AF-102B

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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