API reference

Chloramphenicol

CAS number
56-75-7
Molecular formula
C11H12Cl2N2O5
Molecular weight
323.13 g/mol
Chloramphenicol — 2D structure
2D structure (PubChem)

About this molecule

An antibiotic first isolated from cultures of Streptomyces venezuelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106) The FDA has withdrawn all oral drug products containing chloramphenicol, due to the high risk of fatal aplastic anemia associated with this specific route of administration.

Source: DrugBank, via PubChem.

Identifiers

IUPAC name
2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
InChIKey
WIIZWVCIJKGZOK-RKDXNWHRSA-N
SMILES
C1=CC(=CC=C1[C@H]([C@@H](CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]
Other CAS numbers recorded
125440-98-4 · 2787-09-9
PubChem CID
5959

Also known as

chloramphenicol · Chlornitromycin · Levomycetin · Chlorocid · Levomicetina · Chloroamphenicol · Globenicol · Alficetyn

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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