API reference

Ciclopirox

CAS number
29342-05-0
Molecular formula
C12H17NO2
Molecular weight
207.27 g/mol
Ciclopirox — 2D structure
2D structure (PubChem)

About this molecule

Ciclopirox is a synthetic, broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. Ciclopirox exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-factors for enzymes. This may lead to a loss of activity of enzymes that are essential for cellular metabolism, organization of cell wall structure and other crucial cell functions. In addition, ciclopirox exerts its anti-inflammatory activity by inhibiting 5-lipoxygenase and cyclooxygenase (COX).

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one
InChIKey
SCKYRAXSEDYPSA-UHFFFAOYSA-N
SMILES
CC1=CC(=O)N(C(=C1)C2CCCCC2)O
PubChem CID
2749

Also known as

Loprox · Penlac · Ciclopiroxum · HOE 296b · 2(1H)-Pyridinone, 6-cyclohexyl-1-hydroxy-4-methyl- · cyclopirox · HOE-296b · 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone

Related entries in the range

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