API reference
Cilastatin sodium
- CAS number
- 81129-83-1
- Molecular formula
- C16H25N2NaO5S
- Molecular weight
- 380.4 g/mol
About this molecule
Cilastatin Sodium is the sodium salt form of cilastatin, a renal dehydropeptidase inhibitor, that can be used to inhibit the activity of renal dehydropeptidase. Upon administration of cilastatin sodium, cilastatin targets, binds to and inhibits the activity of renal dehydropeptidase. This reduces the breakdown of drugs, such as the broad spectrum beta-lactam carbapenem imipenem, by renal dehydropeptidase, and thereby increases the activity and therapeutic effect of such drugs that would otherwise be metabolized by renal dehydropeptidase.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- sodium (Z)-7-[(2R)-2-amino-2-carboxyethyl]sulfanyl-2-[[(1S)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoate
- InChIKey
- QXPBTTUOVWMPJN-QBNHLFMHSA-M
- SMILES
- CC1(C[C@@H]1C(=O)N/C(=C\CCCCSC[C@@H](C(=O)O)N)/C(=O)[O-])C.[Na+]
- PubChem CID
- 23663403
Also known as
Cilastatin sodium · Cilastatin sodium salt · RECARBRIO COMPONENT CILASTATIN SODIUM · Sodium, Cilastatin · Cilastatin Monosodium Salt · Monosodium Salt, Cilastatin · Salt, Cilastatin Monosodium · CILASTATIN Na
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