API reference

Cilostazol

CAS number
73963-72-1
Molecular formula
C20H27N5O2
Molecular weight
369.5 g/mol
Cilostazol — 2D structure
2D structure (PubChem)

About this molecule

Cilostazol is a quinolinone derivative and cellular phosphodiesterase inhibitor, more specific for phosphodiesterase III (PDE III). Although the exact mechanism of action of is unknown, cilostazol and its metabolites appears to inhibit PDE III activity, thereby suppressing cyclic adenosine monophosphate (cAMP) degradation. This results in an increase in cAMP in platelets and blood vessels, leading to inhibition of platelet aggregation and vasodilation.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
6-[4-(1-cyclohexyltetrazol-5-yl)butoxy]-3,4-dihydro-1H-quinolin-2-one
InChIKey
RRGUKTPIGVIEKM-UHFFFAOYSA-N
SMILES
C1CCC(CC1)N2C(=NN=N2)CCCCOC3=CC4=C(C=C3)NC(=O)CC4
PubChem CID
2754

Also known as

cilostazol · Pletal · Cilostazole · Pletaal · Cilostazolum · OPC-21 · OPC 21 · Cilostazol (USAN:USP:INN:BAN:JAN)

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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