API reference
Cinnarizine
- CAS number
- 298-57-7
- Molecular formula
- C26H28N2
- Molecular weight
- 368.5 g/mol
About this molecule
First synthesized by Janssen Pharmaceuticals in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and motion sickness. Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system to interfere with the signal transmission between vestibular apparatus of the inner ear and the vomiting centre of the hypothalamus. Cinnarizine could be also viewed as a nootropic drug because of its vasorelaxating abilities (due to calcium channel blockage), which happen mostly in brain. Combination use of cinnarizine with other nootropics, such as [piracetam] resulted in enhanced effect of boosting brain oxygen supply.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- 1-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine
- InChIKey
- DERZBLKQOCDDDZ-JLHYYAGUSA-N
- SMILES
- C1CN(CCN1C/C=C/C2=CC=CC=C2)C(C3=CC=CC=C3)C4=CC=CC=C4
- Other CAS numbers recorded
- 16699-20-0
- PubChem CID
- 1547484
Also known as
cinnarizine · Stugeron · Dimitron · Folcodal · Labyrin · Midronal · Mitronal · Stutgeron
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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