API reference

Clofazimine

CAS number
2030-63-9
Molecular formula
C27H22Cl2N4
Molecular weight
473.4 g/mol
Clofazimine — 2D structure
2D structure (PubChem)

About this molecule

Clofazimine is 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients. It has a role as a non-steroidal anti-inflammatory drug, a leprostatic drug and a dye. It is a member of phenazines and a member of monochlorobenzenes.

Source: ChEBI, via PubChem.

Identifiers

IUPAC name
N,5-bis(4-chlorophenyl)-3-propan-2-yliminophenazin-2-amine
InChIKey
WDQPAMHFFCXSNU-UHFFFAOYSA-N
SMILES
CC(C)N=C1C=C2C(=NC3=CC=CC=C3N2C4=CC=C(C=C4)Cl)C=C1NC5=CC=C(C=C5)Cl
Other CAS numbers recorded
2458811-14-6
PubChem CID
2794

Also known as

clofazimine · Lamprene · Chlofazimine · Clofazimina · Clofaziminum · N,5-bis(4-chlorophenyl)-3-propan-2-yliminophenazin-2-amine · Colfazimine · B663

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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