API reference
Cyclophosphamide
- CAS number
- 50-18-0
- Molecular formula
- C7H15Cl2N2O2P
- Molecular weight
- 261.08 g/mol
About this molecule
Cyclophosphamide Anhydrous is the anhydrous form of cyclophosphamide, a synthetic nitrogen mustard alkylating agent, with antineoplastic and immunosuppressive activities. In the liver, cyclophosphamide is converted to active metabolites including phosphoramide mustard, which binds to and crosslinks DNA and RNA, thereby inhibiting DNA replication and protein synthesis. This agent, at low doses, is also a potent immunosuppressant primarily by depleting T-regulatory cells.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- N,N-bis(2-chloroethyl)-2-oxo-1,3,2lambda5-oxazaphosphinan-2-amine
- InChIKey
- CMSMOCZEIVJLDB-UHFFFAOYSA-N
- SMILES
- C1CNP(=O)(OC1)N(CCCl)CCCl
- Other CAS numbers recorded
- 173547-45-0
- PubChem CID
- 2907
Also known as
cyclophosphamide · Cytoxan · Cyclophosphamid · Cyclophosphane · Endoxan · Clafen · Cyclophosphan · Cytophosphan
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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