API reference
Cyclosporine
- CAS number
- 59865-13-3
- Molecular formula
- C62H111N11O12
- Molecular weight
- 1,202.6 g/mol
About this molecule
Cyclosporin A is a cyclic nonribosomal peptide of eleven amino acids; an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system, and therefore the risk of organ rejection. Also causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle. It has a role as an anticoronaviral agent, a geroprotector, a metabolite, an immunosuppressive agent, an antifungal agent, an antirheumatic drug, an EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor, an anti-asthmatic drug, a dermatologic drug and a carcinogenic agent.
Source: ChEBI, via PubChem.
Identifiers
- IUPAC name
- (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
- InChIKey
- PMATZTZNYRCHOR-CGLBZJNRSA-N
- SMILES
- CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
- Other CAS numbers recorded
- 104250-72-8
- PubChem CID
- 5284373
Also known as
cyclosporin A · Ciclosporin · cyclosporine · Sandimmune · Neoral · Sandimmun · Ciclosporine · Cyclosporine A
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
Tell us the grade, the quantity and the market.
Send the molecule or ingredient, the specification and the destination. We reply from Tehran with the questions, the documents and the next step.