API reference
Darunavir ethanolate
- CAS number
- 635728-49-3
- Molecular formula
- C29H43N3O8S
- Molecular weight
- 593.7 g/mol
About this molecule
Darunavir Ethanolate is the ethanolate form of darunavir, a human immunodeficiency virus type 1 (HIV-1) protease nonpeptidic inhibitor, with activity against HIV. Upon oral administration, darunavir selectively targets and binds to the active site of HIV-1 protease, and inhibits the dimerization and catalytic activity of HIV-1 protease. This inhibits the proteolytic cleavage of viral Gag and Gag-Pol polyproteins in HIV-infected cells. This inhibition leads to the production of immature, non-infectious viral proteins that are unable to form mature virions, and prevents HIV replication.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- [(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate;ethanol
- InChIKey
- QWSHKNICRJHQCY-VBTXLZOXSA-N
- SMILES
- CCO.CC(C)CN(C[C@H]([C@H](CC1=CC=CC=C1)NC(=O)O[C@H]2CO[C@@H]3[C@H]2CCO3)O)S(=O)(=O)C4=CC=C(C=C4)N
- Other CAS numbers recorded
- 635728-39-1
- PubChem CID
- 23725083
Also known as
Darunavir ethanolate · Rezolsta · Darunavir monoethanolate · Tmc114 ethanolate · Darunavir (as ethanolate) · PREZCOBIX COMPONENT DARUNAVIR ETHANOLATE · 864-065-4 · Darunavir (Ethanolate)
Related entries in the range
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