API reference

DAUNORUBICIN HCl

CAS number
23541-50-6
Molecular formula
C27H30ClNO10
Molecular weight
564 g/mol
DAUNORUBICIN HCl — 2D structure
2D structure (PubChem)

About this molecule

Daunorubicin is only found in individuals that have used or taken this drug. It is a very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms. [PubChem]Daunorubicin has antimitotic and cytotoxic activity through a number of proposed mechanisms of action: Daunorubicin forms complexes with DNA by intercalation between base pairs, and it inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the ligation-religation reaction that topoisomerase II catalyzes.

Source: Toxin and Toxin Target Database (T3DB), via PubChem.

Identifiers

IUPAC name
(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride
InChIKey
GUGHGUXZJWAIAS-QQYBVWGSSA-N
SMILES
C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)C)O)N)O.Cl
PubChem CID
62770

Also known as

DAUNORUBICIN HYDROCHLORIDE · DAUNORUBICIN HCL · Daunomycin hydrochloride · Daunoblastina · Rubidomycin hydrochloride · Ondena · Daunomycin chlorohydrate · Daunomycin, hydrochloride

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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