API reference
Desflurane
- CAS number
- 57041-67-5
- Molecular formula
- C3H2F6O
- Molecular weight
- 168.04 g/mol
About this molecule
Desflurane is a highly fluorinated methyl ethyl ether used for maintenance of general anaesthesia. Volatile agents such as desflurane may activate GABA channels and hyperpolarize cell membranes. In addition, they may inhibit certain calcium channels and therefore prevent release of neurotransmitters and inhibit glutamate channels. Volatile anesthetics easily partition into cellular membranes and could expand the volume of the cell membrane and subsequently distort channels necessary for sodium ion flux and the development of action potentials necessary for synaptic transmission. Desflurane preconditions human myocardium against ischemia through activation of mitochondrial K(ATP) channels, adenosine A1 receptor, and alpha and beta adrenoceptors.
Source: Toxin and Toxin Target Database (T3DB), via PubChem.
Identifiers
- IUPAC name
- 2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane
- InChIKey
- DPYMFVXJLLWWEU-UHFFFAOYSA-N
- SMILES
- C(C(F)(F)F)(OC(F)F)F
- PubChem CID
- 42113
Also known as
Suprane · 2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane · Desflurano · difluoromethyl 1,2,2,2-tetrafluoroethyl ether · Desfluranum · I-653 · I 653 · (+-)-2-Difluoromethyl 1,2,2,2-tetrafluoroethyl ether
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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