API reference
Dexlansoprazole
- CAS number
- 138530-94-6
- Molecular formula
- C16H14F3N3O2S
- Molecular weight
- 369.4 g/mol
About this molecule
Dexlansoprazole is a new-generation proton pump inhibitor (PPI) used for the management of symptoms associated with gastroesophageal reflux disease (GERD) and erosive esophagitis. Dexlansoprazole is the R-enantiomer of [DB00448], which is composed of a racemic mixture of the R- and S-enantiomers. Compared to the older generation of PPIs (which includes [DB00213], [DB00338], and [DB00448]), dexlansoprazole has a unique pharmacokinetic profile due to its delayed-release and dual-delivery release system: This aims to address some limitations of the older-generation PPIs, such as short plasma half-life and the need for meal-associated dosing. Dexlansoprazole inhibits the final step in gastric acid production by blocking the (H+, K+)-ATPase enzyme.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- 2-[(R)-[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methylsulfinyl]-1H-benzimidazole
- InChIKey
- MJIHNNLFOKEZEW-RUZDIDTESA-N
- SMILES
- CC1=C(C=CN=C1C[S@@](=O)C2=NC3=CC=CC=C3N2)OCC(F)(F)F
- PubChem CID
- 9578005
Also known as
dexlansoprazole · (R)-Lansoprazole · Kapidex · dexilant · Dexilant Solutab · r-lansoprazole · TAK-390 · TAK 390
Related entries in the range
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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