API reference
DEXMEDETOMIDINE HCl
- CAS number
- 145108-58-3
- Molecular formula
- C13H17ClN2
- Molecular weight
- 236.74 g/mol
About this molecule
Dexmedetomidine Hydrochloride is the hydrochloride salt form of dexmedetomidine, an imidazole derivate and active d-isomer of medetomidine with analgesic, anxiolytic and sedative activities. Dexmedetomidine selectively binds to and activates presynaptic alpha-2 adrenoceptors located in the brain, thereby inhibiting the release of norepinephrine from synaptic vesicles. This leads to an inhibition of postsynaptic activation of adrenoceptors, which inhibits sympathetic activity, thereby leading to analgesia, sedation and anxiolysis.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole;hydrochloride
- InChIKey
- VPNGEIHDPSLNMU-MERQFXBCSA-N
- SMILES
- CC1=C(C(=CC=C1)[C@H](C)C2=CN=CN2)C.Cl
- PubChem CID
- 6918081
Also known as
Dexmedetomidine hydrochloride · Dexmedetomidine HCL · Dexdomitor · Dexdor · Cepedex · Sedadex · Dexmedesed · Sedexodine
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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