API reference
Dexrazoxane
- CAS number
- 24584-09-6
- Molecular formula
- C11H16N4O4
- Molecular weight
- 268.27 g/mol
About this molecule
Dexrazoxane is a bisdioxopiperazine with iron-chelating, chemoprotective, cardioprotective, and antineoplastic activities. After hydrolysis to an active form that is similar to ethylenediaminetetraacetic acid (EDTA), dexrazoxane chelates iron, limiting the formation of free radical-generating anthracycline-iron complexes, which may minimize anthracycline-iron complex-mediated oxidative damage to cardiac and soft tissues. This agent also inhibits the catalytic activity of topoisomerase II, which may result in tumor cell growth inhibition.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione
- InChIKey
- BMKDZUISNHGIBY-ZETCQYMHSA-N
- SMILES
- C[C@@H](CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2
- PubChem CID
- 71384
Also known as
Dexrazoxane · ICRF-187 · Dextrorazoxane · Dexrazoxano · Dexrazoxanum · ADR-529 · Razoxane, d- · Razoxane, (s)-
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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