API reference
Diazoxide
- CAS number
- 364-98-7
- Molecular formula
- C8H7ClN2O2S
- Molecular weight
- 230.67 g/mol
About this molecule
Diazoxide is a benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies. It has a role as a diuretic, a beta-adrenergic agonist, a bronchodilator agent, a sympathomimetic agent, a vasodilator agent, an antihypertensive agent, a cardiotonic drug, a sodium channel blocker and a K-ATP channel agonist. It is a sulfone, an organochlorine compound and a benzothiadiazine.
Source: ChEBI, via PubChem.
Identifiers
- IUPAC name
- 7-chloro-3-methyl-4H-1lambda6,2,4-benzothiadiazine 1,1-dioxide
- InChIKey
- GDLBFKVLRPITMI-UHFFFAOYSA-N
- SMILES
- CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl
- PubChem CID
- 3019
Also known as
diazoxide · Proglycem · Hyperstat · Hypertonalum · Mutabase · Diazoxido · Diazoxidum · 7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
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