API reference
Diluted isosorbide dinitrate
- CAS number
- 87-33-2
- Molecular formula
- C6H8N2O8
- Molecular weight
- 236.14 g/mol
About this molecule
Isosorbide Dinitrate is the dinitrate salt form of isosorbide, an organic nitrate with vasodilator activity. Isosorbide dinitrate relaxes vascular smooth muscle by formation of the free radical nitric oxide (NO), which is identical to the endothelium-derived relaxing factor (EDRF). NO activates guanylyl cyclase, thereby increasing the synthesis of cGMP within smooth muscle, resulting in dephosphorylation of light chain myosin and relaxation of peripheral arteries and veins. In addition, isosorbide dinitrate relaxes coronary arteries, thereby increasing the blood circulation through the ischemic area. (NCI05)
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- [(3S,3aS,6R,6aS)-3-nitrooxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] nitrate
- InChIKey
- MOYKHGMNXAOIAT-JGWLITMVSA-N
- SMILES
- C1[C@H]([C@@H]2[C@H](O1)[C@H](CO2)O[N+](=O)[O-])O[N+](=O)[O-]
- Other CAS numbers recorded
- 1246815-45-1 · 54650-95-2
- PubChem CID
- 6883
Also known as
ISOSORBIDE DINITRATE · Isordil · Sorbidnitrate · Sorbitrate · Sorbide nitrate · Nitrosorbide · ISDN · Dinitrosorbide
Related entries in the range
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
Tell us the grade, the quantity and the market.
Send the molecule or ingredient, the specification and the destination. We reply from Tehran with the questions, the documents and the next step.