API reference

Dinoprostone

CAS number
363-24-6
Molecular formula
C20H32O5
Molecular weight
352.5 g/mol
Dinoprostone — 2D structure
2D structure (PubChem)

About this molecule

Prostaglandin E2 is a prostaglandin with 2 double bonds that is generated by the action of prostaglandin E synthases on prostaglandin H2. Prostaglandin E2 is a mediator of active inflammation, and has important biologic effects including potent vasodilation, smooth muscle relaxation, stimulation of osteoclast-dependent bone resorption and induction of both pain and fever. It is also used as a vaginal suppository during labor to soften the cervix and promote uterine contractions.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
(Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid
InChIKey
XEYBRNLFEZDVAW-ARSRFYASSA-N
SMILES
CCCCC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1C/C=C\CCCC(=O)O)O)O
Other CAS numbers recorded
22230-04-2
PubChem CID
5280360

Also known as

Prostaglandin E2 · Dinoprostone · PGE2 · Prostin E2 · Prepidil · Cervidil · Minprostin E2 · Propess

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